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EFCAB4B 抗体 (C-Term)

EFCAB4B 适用: 人, 小鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN783785
发货至: 中国
  • 抗原 See all EFCAB4B 抗体
    EFCAB4B (EF-Hand Calcium Binding Domain 4B (EFCAB4B))
    抗原表位
    • 8
    • 8
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 23
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 21
    • 2
    克隆类型
    • 23
    多克隆
    标记
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    This EFCAB4B antibody is un-conjugated
    应用范围
    • 23
    • 13
    • 3
    • 2
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects EFCAB4B at C-term.
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    14 amino acid peptide near the carboxy terminus of human EFCAB4B
    Top Product
    Discover our top product EFCAB4B Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • 抗原
    EFCAB4B (EF-Hand Calcium Binding Domain 4B (EFCAB4B))
    别名
    EFCAB4B (EFCAB4B 产品)
    别名
    CRACR2A antibody, Gm1073 antibody, Gm462 antibody, calcium release activated channel regulator 2A antibody, CRACR2A antibody, Cracr2a antibody
    背景
    EFCAB4B, also known as Calcium release-activated calcium channel regulator 2A, is a novel Ca2+-binding EF-hand protein that is thought to play a key role in store-operated Ca2+ entry in T-cells by regulating CRAC channel activation. EFCAB4B acts as a cytoplasmic calcium-sensor that forms a complex with ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca2+ concentration. A closely related protein, EFCAB4A, is likely to play a similar role as EFCAB4B, but the detailed function of EFCAB4A is still under investigation.Synonyms: EF-hand calcium-binding domain-containing protein 4B, MGC4266
    基因ID
    84766
    NCBI登录号
    NP_001138430
    UniProt
    Q9BSW2
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