NLRP12 抗体 (N-Term)
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Quick Overview for NLRP12 抗体 (N-Term) (ABIN783719)
抗原
See all NLRP12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody detects NALP2 at N-term.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 18 amino acid peptide near the amino terminus of human NALP12
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anti-NLR Family, Pyrin Domain Containing 12 (NLRP12) (AA 1-110) antibody
NLRP12 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4B9 unconjugated
anti-NLR Family, Pyrin Domain Containing 12 (NLRP12) (AA 183-212), (N-Term) antibodyNLRP12 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB33963 unconjugated
anti-NLR Family, Pyrin Domain Containing 12 (NLRP12) antibodyNLRP12 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 12 (NLRP12) (AA 183-212) antibodyNLRP12 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 12 (NLRP12) (AA 862-1062) antibodyNLRP12 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 12 (NLRP12) (Internal Region) antibodyVerified NLRP12 适用: 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 12 (NLRP12) antibodyNLRP12 适用: 小鼠 WB, ELISA 宿主: 小鼠 Monoclonal 228CT4-1-3 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))
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别名
- NALP12
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背景
- NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP12, also known as Monarch-1, has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. NALP12 is thought to act as an attenuating factor of inflammation by suppressing inflammatory responses such as NF-kB activation by TLR-signaling molecules MyD88, IRAK-1, TRAF6 and RIPK1 in activated monocytes. Recent evidence suggests that mutations in NALP12 result in hereditary periodic fever syndromes.Synonyms: LRR and PYD domains-containing protein 12, Monarch-1, NACHT, NLRP12, PYPAF7, PYRIN-containing APAF1-like protein 7, RNO, Regulated by nitric oxide
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基因ID
- 91662
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NCBI登录号
- NP_150639
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UniProt
- P59046
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途径
- Positive Regulation of Endopeptidase Activity, Inflammasome
抗原
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