ATG13 抗体 (C-Term)
Quick Overview for ATG13 抗体 (C-Term) (ABIN783663)
抗原
See all ATG13 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 15 amino acid peptide near the carboxy terminus of human ATG13
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anti-Autophagy Related 13 (ATG13) (AA 281-480) antibody
ATG13 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Autophagy Related 13 (ATG13) (AA 339-550) antibodyATG13 适用: 人 ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 3E4C8 unconjugated
anti-Autophagy Related 13 (ATG13) (AA 339-550) antibodyATG13 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 6B2E12 unconjugated
anti-Autophagy Related 13 (ATG13) (AA 51-150) antibodyATG13 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Autophagy Related 13 (ATG13) (AA 315-517) antibodyATG13 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Autophagy Related 13 (ATG13) (AA 318-517) antibodyATG13 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Autophagy Related 13 (ATG13) (pSer318) antibodyATG13 适用: 人 WB, ELISA, DB, FACS 宿主: 兔 Polyclonal unconjugated
anti-Autophagy Related 13 (ATG13) (AA 1-30) antibodyATG13 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Autophagy Related 13 (ATG13) (AA 333-362) antibodyATG13 适用: 人 WB 宿主: 兔 Polyclonal RB40773 unconjugated
anti-Autophagy Related 13 (ATG13) (AA 1-30), (N-Term) antibodyATG13 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB25736 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at -20 °C.
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- ATG13 (Autophagy Related 13 (ATG13))
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别名
- KIAA0652
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背景
- Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein ATG1. ATG13 forms a complex with ULK1 and ULK2, the mammalian homologs of ATG1, and with FIP200. This complex is a target of TOR phosphorylation under normal conditions, inhibition of TOR by rapamycin or leucine deprivation leads to dephosphorylation of ATG13, ULK1 and ULK2, which then leads to autophagy. Knockdown of ATG13 inhibits autophagosome formation.Synonyms: UPF0630 protein KIAA0652
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基因ID
- 9776
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NCBI登录号
- NP_001136145
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UniProt
- O75143
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途径
- PI3K-Akt Signaling, Autophagy
抗原
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