FREM2 抗体 (Center)
Quick Overview for FREM2 抗体 (Center) (ABIN783636)
抗原
See all FREM2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Center
-
特异性
- This antibody reacts with Human and Mouse FREM2 and is predicted to not cross-react with other FRAS members. This antibody recognizes both isoforms of FREM2.
-
纯化方法
- Affinity chromatography purified via peptide column
-
免疫原
- 19 amino acid peptide near the center of Human FREM2
-
-
anti-Fras1 Related Extracellular Matrix Protein 2 (FREM2) (Internal Region) antibody
FREM2 适用: 人, 小鼠 ELISA, WB, ICC, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Fras1 Related Extracellular Matrix Protein 2 (FREM2) (AA 1986-2127) antibodyFREM2 适用: 人 ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fras1 Related Extracellular Matrix Protein 2 (FREM2) (AA 47-300) antibodyFREM2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- PBS, 0.02 % Sodium Azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- FREM2 (Fras1 Related Extracellular Matrix Protein 2 (FREM2))
-
别名
- FREM2
-
背景
- FREM2 is a member of the FRAS1-related extracellular matrix protein family and like FREM1, mutations in the FREM2 gene are associated with Fraser syndrome. FREM2 localizes to the basement membrane, forming a ternary complex that plays a role in epidermal-dermal interactions during morphogenetic processes and is thought to be required for maintaining the integrity of the skin epithelium and the differentiated state of renal epithelia. The FREM2 gene is one of several genes whose transcription is affecteded by TFAP2C, a transcription factor involved in mammary development, differentiation, and oncogenesis.Synonyms: ECM3 homolog, FRAS1-related extracellular matrix protein 2
-
基因ID
- 341640
-
NCBI登录号
- NP_997244
-
UniProt
- Q5SZK8
抗原
-
