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SIRT4 抗体 (N-Term)

This anti-SIRT4 antibody is a 小鸡 多克隆 antibody detecting SIRT4 in WB 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN783612
发货至: 中国

Quick Overview for SIRT4 抗体 (N-Term) (ABIN783612)

抗原

See all SIRT4 抗体
SIRT4 (Sirtuin 4 (SIRT4))

适用

  • 54
  • 36
  • 26
  • 5
  • 5
  • 5
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 55
  • 8
  • 1
  • 1
小鸡

克隆类型

  • 59
  • 6
多克隆

标记

  • 33
  • 9
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SIRT4 antibody is un-conjugated

应用范围

  • 53
  • 21
  • 16
  • 7
  • 4
  • 4
  • 3
  • 2
  • 2
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 12
    • 8
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse, rat

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    17 amino acid peptide near the amino terminus of human SIRT4
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store the antibody (in aliquots) at -20 °C.
  • 抗原

    SIRT4 (Sirtuin 4 (SIRT4))

    别名

    SIRT4

    背景

    The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT4 localizes to mitochondria, inhibits glutamate dehydrogenase, and is thought to be involved in the regulation of insulin secretion.Synonyms: NAD-Dependent ADP-Ribosyltransferase Sirtuin-4, SIR2-like 4, SIR2L4, SIRT-4, sirtuin (silent mating type information regulation 2 homolog) 4 (S. cerevisiae), sirtuin 4, sirtuin type 4, sirtuin-4

    基因ID

    23409

    NCBI登录号

    NP_036372

    UniProt

    Q9Y6E7

    途径

    Negative Regulation of Hormone Secretion
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