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NSMCE2 抗体 (C-Term)

This anti-NSMCE2 antibody is a 兔 多克隆 antibody detecting NSMCE2 in WB 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN783606
发货至: 中国

Quick Overview for NSMCE2 抗体 (C-Term) (ABIN783606)

抗原

See all NSMCE2 抗体
NSMCE2 (E3 SUMO-Protein Ligase NSE2 (NSMCE2))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

  • 24
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多克隆

标记

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This NSMCE2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 7
    • 2
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    C-Term

    交叉反应 (详细)

    Species reactivity (tested):Human, Mouse, Rat

    纯化方法

    Immunoaffinity Chromatography

    免疫原

    15 amino acid peptide near the carboxy terminus of Human MMS21
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.02 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store the antibody (in aliquots) at -20 °C.
  • 抗原

    NSMCE2 (E3 SUMO-Protein Ligase NSE2 (NSMCE2))

    别名

    NSMCE2

    背景

    MMS21, also known as NSE2, is a SUMO ligase that in combination with the SMC5/6 complex is required for the prevention of DNA damage induced apoptosis by facilitating DNA repair in human cells. MMS21-dependent sumoylation is integral and important to the cohesion mechanism and mitotic progression, this function appears to be independent of SMC6. MMS21 mediates SUMO attachment to various proteins such as SMC6L1 and TRAX, and possibly the cohesin components RAD21 and STAG2.Synonyms: C8orf36, E3 SUMO-protein ligase NSE2, MMS21

    基因ID

    286053

    NCBI登录号

    NP_775956

    UniProt

    Q96MF7
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