PIAS4 抗体 (N-Term)
Quick Overview for PIAS4 抗体 (N-Term) (ABIN783598)
抗原
See all PIAS4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 19 amino acid peptide near the amino terminus of human PIAS4
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anti-Protein Inhibitor of Activated STAT, 4 (PIAS4) (C-Term) antibody
PIAS4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 4 (PIAS4) (AA 48-79), (N-Term) antibodyPIAS4 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB0680 unconjugated
anti-Protein Inhibitor of Activated STAT, 4 (PIAS4) (AA 66-241) antibodyPIAS4 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 4 (PIAS4) (AA 1-510) antibodyPIAS4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 4 (PIAS4) (AA 44-60) antibodyPIAS4 适用: 人, 猴 WB, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 4 (PIAS4) (N-Term) antibodyPIAS4 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 斑马鱼, 猴, Bat, 小鸡, Pig, Hamster, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 4 (PIAS4) (AA 60-260) antibodyPIAS4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 4 (PIAS4) (AA 471-499), (C-Term) antibodyPIAS4 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB00682 unconjugated
anti-Protein Inhibitor of Activated STAT, 4 (PIAS4) (C-Term) antibodyPIAS4 适用: 人, Cow WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 4 (PIAS4) (N-Term) antibodyPIAS4 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at -20 °C.
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- PIAS4 (Protein Inhibitor of Activated STAT, 4 (PIAS4))
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别名
- PIAS4
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背景
- The PIAS (protein inhibitor of activated STAT) proteins play a crucial role as transcriptional coregulators in various cellular pathways, including the STAT, p53 and the steroid hormone signaling pathway. The PIAS protein family includes at least five evolutionarily conserved genes, including PIAS4. The major function of the PIAS proteins is the control of gene transcription and can also act as small ubiquitin-like-modifier (SUMO) E3 ligases. PIAS4 interacts with p53 and blocks its ability to induce Bax and p21 transcription. PIAS4 is also important in the control of the ubiquitin-dependent proteasomal degradation of the Ets-1 transcription factor. PIAS4 has been implicated in the DNA-damage response pathway and is thought to work in combination with PIAS1 for the productive association of 53BP1, BRCA1 and RNF168.Synonyms: E3 SUMO-protein ligase PIAS4, PIAS-gamma, PIASG, PIASy, Protein inhibitor of activated STAT protein 4, Protein inhibitor of activated STAT protein gamma
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基因ID
- 51588
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NCBI登录号
- NP_056981
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UniProt
- Q8N2W9
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途径
- JAK/STAT Signaling, Interferon-gamma Pathway, Positive Regulation of Response to DNA Damage Stimulus
抗原
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