Transportin 3 抗体 (N-Term)
Quick Overview for Transportin 3 抗体 (N-Term) (ABIN783562)
抗原
See all Transportin 3 (TNPO3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody detects Transportin-3 (TNPO3) at N-term.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 18 amino acid peptide from near the amino terminus of human TNPO3
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anti-Transportin 3 (TNPO3) (Internal Region) antibody
TNPO3 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transportin 3 (TNPO3) antibodyTNPO3 适用: 人 WB, ICC, DB 宿主: 小鼠 Monoclonal 3152C2a unconjugated
anti-Transportin 3 (TNPO3) (AA 382-458) antibodyTNPO3 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Transportin 3 (TNPO3) (C-Term) antibodyTNPO3 适用: 人, 小鼠, 大鼠, Cow, Pig, 犬, 豚鼠, 马, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- Transportin 3 (TNPO3)
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别名
- Transportin-3 (TNPO3)
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背景
- TNPO3 is a member of the importin beta/transportin family of nuclear import receptors and is specific for the essential splicing factors termed SR proteins, binding specifically and directly to the arginine/serine (RS)-rich domains of these proteins. Further experiments demonstrated that this interaction occurs only when these RS domains are phosphorylated. More recently, TNPO3 was identified as an HIV dependency factor (HDF) and that depletion of TNPO3 resulted in HIV inhibition after reverse transcription but before integration, suggesting that TNPO3 may be an important drug target in HIV treatment. At least three isoforms of TNPO3 are known to exist.Synonyms: IPO12, Imp12, Importin-12, TRN-SR, Transportin-SR
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基因ID
- 23534
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NCBI登录号
- NP_001177957
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UniProt
- Q9Y5L0
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途径
- Protein targeting to Nucleus
抗原
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