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Caspase 7 抗体 (N-Term)

This anti-Caspase 7 antibody is a 兔 多克隆 antibody detecting Caspase 7 in WB, IHC (p) 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN783546
发货至: 中国

Quick Overview for Caspase 7 抗体 (N-Term) (ABIN783546)

抗原

See all Caspase 7 (CASP7) 抗体
Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))

适用

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  • 1
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人, 小鼠, 大鼠

宿主

  • 99
  • 12
  • 1

克隆类型

  • 97
  • 15
多克隆

标记

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This Caspase 7 antibody is un-conjugated

应用范围

  • 103
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  • 4
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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 16
    • 15
    • 9
    • 7
    • 3
    • 3
    • 3
    • 3
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    • 2
    • 2
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    • 1
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    N-Term

    特异性

    This antibody detects Caspase-7 at N-term.

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse, rat

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    16 amino acid peptide from near the amino-terminus of human Caspase-7
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • 抗原

    Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))

    别名

    Caspase-7

    背景

    Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens (reviewed in 1 and 2). The apoptotic subfamily can be further divided into initiator caspases, which are activated in response to death signals, and executioner caspases, which are activated by the initiator caspases and are responsible for cleavage of cellular substrates that ultimately lead to cell death (reviewed in 3). Caspase-7 is an executioner caspase that was identified based on its homology with caspases 1 and 3, as well as the C. elegans cell death protein CED-3 (4). Alternative splicing of Caspase-7 mRNA results in the production of 3 distinct isoforms (4). Caspase-7 activity can be directly inhibited by XIAP expression (5).Synonyms: Apoptotic protease Mch-3, CASP-7, CASP7, CMH-1, ICE-like apoptotic protease 3, MCH3

    基因ID

    840

    NCBI登录号

    NP_001218

    UniProt

    P55210

    途径

    Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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