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FOXO3 抗体 (N-Term)

This anti-FOXO3 antibody is a 兔 多克隆 antibody detecting FOXO3 in WB 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN783540
发货至: 中国

Quick Overview for FOXO3 抗体 (N-Term) (ABIN783540)

抗原

See all FOXO3 抗体
FOXO3 (Forkhead Box O3 (FOXO3))

适用

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人, 小鼠, 大鼠

宿主

  • 125
  • 6
  • 1
  • 1

克隆类型

  • 110
  • 23
多克隆

标记

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This FOXO3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 38
    • 9
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    • 1
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    • 1
    • 1
    • 1
    • 1
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    N-Term

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse, rat

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    18 amino acid peptide near the amino terminus of human FOXO3
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store the antibody (in aliquots) at -20 °C.
  • 抗原

    FOXO3 (Forkhead Box O3 (FOXO3))

    别名

    FOXO3 / FKHRL1

    背景

    FOXO3 is a ubiquitously expressed 75 kDa protein member of a subfamily of the forkhead homeotic gene family of transcription factors and shuttles between the cytoplasm and nucleus. FOXO transcription factors are key players of cell fate decisions, metabolism, stress resistance, tumor suppression and are regulated by growth factors, oxidative stress or nutrient deprivation. FOXO3 is involved with mTOR in the regulation of autophagy in skeletal muscle, and activates protein degradation in atrophying muscle cells. FOXO3 has also been implicated in several neurodegenerative disorders including aging, neuromuscular disease, systemic lupus erythmatosus, stroke and diabetic complications.Synonyms: AF6q21 protein, FOXO3A, Forkhead box protein O3, Forkhead in rhabdomyosarcoma-like 1

    基因ID

    2309

    NCBI登录号

    NP_001446

    UniProt

    O43524

    途径

    Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis
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