SIK2 抗体 (Center)
Quick Overview for SIK2 抗体 (Center) (ABIN783466)
抗原
See all SIK2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Center
-
特异性
- This antibody detects SIK2 at Center. SIK2 antibody is predicted to not cross-react with other SIK protein family members.
-
交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
-
纯化方法
- Affinity chromatography purified via peptide column
-
免疫原
- 16 amino acid peptide near the center of human SIK2
-
-
anti-Salt-Inducible Kinase 2 (SIK2) (AA 467-576) antibody
SIK2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4C6 unconjugated
anti-Salt-Inducible Kinase 2 (SIK2) (AA 100-150) antibodySIK2 适用: 人, 小鼠, 大鼠, Cow, 犬 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Salt-Inducible Kinase 2 (SIK2) (AA 467-576) antibodySIK2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4H6 unconjugated
anti-Salt-Inducible Kinase 2 (SIK2) (AA 674-916) antibodySIK2 适用: 小鼠 WB, IP, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Salt-Inducible Kinase 2 (SIK2) (AA 281-330) antibodySIK2 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Salt-Inducible Kinase 2 (SIK2) (AA 827-926) antibodySIK2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Salt-Inducible Kinase 2 (SIK2) (AA 655-925) antibodySIK2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
缓冲液
- PBS containing 0.02 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
-
-
- SIK2 (Salt-Inducible Kinase 2 (SIK2))
-
别名
- SIK2
-
背景
- Salt-inducible kinase 2 (SIK2), like its closely related homolog SIK1, belongs AMPK subfamily of the Ser/Thr protein kinase family and negatively regulates CRE-binding protein (CREB) activity by phosphorylating the CREB-specific coactivator transducer of regulated CREB activity (TORC). SIK2 is thought to be part of a signaling cascade that regulates the expression and activity of the insulin-induced genes PGC-1?alpha and UCP-1 in brown adipocytes, impairment of which has been implicated in obesity and insulin resistance in human and animal models. SIK2 has also been reported as a key regulator for neuronal survival after ischemia, suppressing CREB-mediated gene expression after oxygen-glucose deprivation.Synonyms: QIK, Qin-induced kinase, SIK-2, SNF1LK2, Salt-inducible protein kinase 2, Serine/threonine-protein kinase SIK2, Serine/threonine-protein kinase SNF1-like kinase 2
-
基因ID
- 23235
-
NCBI登录号
- NP_056006
-
UniProt
- Q9H0K1
抗原
-
