SIK1 抗体 (Center)
(1 reference)Quick Overview for SIK1 抗体 (Center) (ABIN783464)
抗原
See all SIK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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特异性
- This antibody detects SIK1 at Center. Two isoforms of SIK1 are known to exist, this antibody will detect both isoforms. SIK1 antibody is predicted to not cross-react with other SIK protein family members.
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交叉反应 （详细）
- Species reactivity (tested):Human
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 18 amino acid peptide near the center of human SIK1
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anti-Salt-Inducible Kinase 1 (SIK1) (AA 1-783) antibody
SIK1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Salt-Inducible Kinase 1 (SIK1) (AA 1-100) antibodySIK1 适用: 人 ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2C12 unconjugated
anti-Salt-Inducible Kinase 1 (SIK1) (AA 492-750) antibodySIK1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Salt-Inducible Kinase 1 (SIK1) (N-Term) antibodySIK1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Salt-Inducible Kinase 1 (SIK1) (AA 567-597), (C-Term) antibodySIK1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB3576 unconjugated
anti-Salt-Inducible Kinase 1 (SIK1) (AA 1-101) antibodySIK1 适用: 人 ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2C12 unconjugated
anti-Salt-Inducible Kinase 1 (SIK1) (AA 1-783) antibodySIK1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Salt-Inducible Kinase 1 (SIK1) (N-Term) antibodySIK1 适用: 人, 马, Cow, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Salt-Inducible Kinase 1 (SIK1) (N-Term) antibodySIK1 适用: 人, 小鼠, 大鼠, 马, 犬, 豚鼠, Cow, Pig, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Salt-Inducible Kinase 1 (SIK1) (AA 51-150) antibodySIK1 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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: "CISD2 associated with proliferation indicates negative prognosis in patients with hepatocellular carcinoma." in: International journal of clinical and experimental pathology, Vol. 8, Issue 10, pp. 13725-38, (2016) (PubMed).
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: "CISD2 associated with proliferation indicates negative prognosis in patients with hepatocellular carcinoma." in: International journal of clinical and experimental pathology, Vol. 8, Issue 10, pp. 13725-38, (2016) (PubMed).
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- SIK1 (Salt-Inducible Kinase 1 (SIK1))
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别名
- SIK1
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背景
- Salt-inducible kinase 1 (SIK1), also known as SNF1LK or MSK, plays a role in histone modification and G2/M cell cycle regulation. It is a 783 amino acid protein that contains one UBA domain and belongs to the Ser/Thr protein kinase family (AMPK subfamily). Localized to both the nucleus and the cytoplasm, SIK1 is a class II HDAC kinase that uses magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of target proteins and is thought to be important for the early stages of skeletal muscle growth and myocardial cell differentiation.Synonyms: SIK, SIK-1, SNF1LK, Salt-inducible protein kinase 1, Serine/threonine-protein kinase SIK1, Serine/threonine-protein kinase SNF1-like kinase 1
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基因ID
- 150094
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NCBI登录号
- NP_775490
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UniProt
- P57059
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途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process
抗原
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