PRR5L 抗体 (Center)
This anti-PRR5L antibody is a 兔 多克隆 antibody detecting PRR5L in WB 和 EIA. Suitable for 人.
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Quick Overview for PRR5L 抗体 (Center) (ABIN783444)
抗原
See all PRR5L 抗体
PRR5L
(Proline Rich 5 Like (PRR5L))
适用
人
宿主
兔
克隆类型
多克隆
标记
This PRR5L antibody is un-conjugated
应用范围
Western Blotting (WB), Enzyme Immunoassay (EIA)
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抗原表位
- Center
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特异性
- This antibody detects PRR5L at Center. At least three isoforms of PRR5L are known to exist, this antibody will recognize only isoforms a and b. PRR5L antibody will not cross-react with PPR5.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 17 amino acid peptide near the center of human PRR5L
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- PRR5L (Proline Rich 5 Like (PRR5L))
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别名
- PRR5L
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背景
- Proline-rich protein 5-like (PRR5L), also known as Protor-2, is structurally similar to PRR5 and also binds to the mTOR complex 2 (mTORC2). PRR5L is not required for mTORC2 integrity or kinase activity, but dissociates from mTORC2 upon knockdown of tuberous sclerosis complex 1 (TSC1) and TSC2. Knockdown of PRR5L reduced apoptosis in mTORC2 deficient cells as well as cells where mTOR was active, suggesting that mTORC2-dissociated PRR5L may promote apoptosis, and thus play a role in the balance between cell growth and cell death.Synonyms: FLJ14213, PROTOR2, Proline-rich protein 5-like, Protein observed with Rictor-2
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基因ID
- 79899
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NCBI登录号
- NP_001153639
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UniProt
- Q6MZQ0
抗原
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