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PRR5L 抗体 (AA 220-270)

PRR5L 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6991524
发货至: 中国
  • 抗原 See all PRR5L 抗体
    PRR5L (Proline Rich 5 Like (PRR5L))
    抗原表位
    • 1
    • 1
    AA 220-270
    适用
    人, 小鼠
    宿主
    • 3
    克隆类型
    • 3
    多克隆
    标记
    • 3
    This PRR5L antibody is un-conjugated
    应用范围
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    At least three isoforms of PRR5L are known to exist, this antibody will recognize only isoforms a and b. PRR5L antibody will not cross-react with PPR5.
    纯化方法
    PRR5L Antibody is affinity chromatography purified via peptide column.
    免疫原
    PRR5L antibody was raised against a 17 amino acid synthetic peptide near the center of human PRR5L. The immunogen is located within amino acids 220 - 270 of PRR5L.
    亚型
    IgG
  • 应用备注
    PRR5L antibody can be used for detection of PRR5L by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in mouse samples, Immunocytochemistry in human samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PRR5L Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    PRR5L antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    PRR5L (Proline Rich 5 Like (PRR5L))
    别名
    PRR5L (PRR5L 产品)
    别名
    PROTOR2 antibody, 2600010E01Rik antibody, 4833411O04Rik antibody, Protor-2 antibody, Protor2 antibody, RGD1309969 antibody, PRR5L antibody, FLJ14213 antibody, proline rich 5 like antibody, PRR5L antibody, Prr5l antibody, prr5l antibody
    背景
    PRR5L Antibody: Proline-rich protein 5-like (PRR5L), also known as Protor-2, is structurally similar to PRR5 and also binds to the mTOR complex 2 (mTORC2). PRR5L is not required for mTORC2 integrity or kinase activity, but dissociates from mTORC2 upon knockdown of tuberous sclerosis complex 1 (TSC1) and TSC2. Knockdown of PRR5L reduced apoptosis in mTORC2 deficient cells as well as cells where mTOR was active, suggesting that mTORC2-dissociated PRR5L may promote apoptosis, and thus play a role in the balance between cell growth and cell death.
    基因ID
    79899
    NCBI登录号
    NP_001153639
    UniProt
    Q6MZQ0
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