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DYRK2 抗体 (C-Term)

DYRK2 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN783436
发货至: 中国
  • 抗原 See all DYRK2 抗体
    DYRK2 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2))
    抗原表位
    • 15
    • 10
    • 8
    • 8
    • 7
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 47
    • 32
    • 22
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 60
    • 7
    • 1
    克隆类型
    • 61
    • 7
    多克隆
    标记
    • 26
    • 6
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This DYRK2 antibody is un-conjugated
    应用范围
    • 61
    • 38
    • 32
    • 13
    • 13
    • 9
    • 5
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects DYRK2 at C-term. Two isoforms of DYRK2 are known to exist, this antibody will recognize both isoforms. DYRK2 antibody will not cross-react with other DYRK family members.
    交叉反应 (详细)
    Species reactivity (tested):Human
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    18 amino acid peptide near the carboxy terminus of human DYRK2
    Top Product
    Discover our top product DYRK2 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • 抗原
    DYRK2 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2))
    别名
    DYRK2 (DYRK2 产品)
    别名
    DYRK2 antibody, fc18c09 antibody, si:ch211-266a5.8 antibody, wu:fa09g03 antibody, wu:fc18c09 antibody, 1810038L18Rik antibody, dual specificity tyrosine phosphorylation regulated kinase 2 antibody, dual specificity tyrosine-phosphorylation-regulated kinase 2 antibody, dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 antibody, DYRK2 antibody, CpipJ_CPIJ014802 antibody, dyrk2 antibody, Dyrk2 antibody
    背景
    DYRK2 is a member of the dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family that is thought to be involved in cellular proliferation and apoptosis. Under normal conditions, nuclear but not cytoplasmic DYRK2 is ubiquitinated by MDM2, leading to its constitutive degradation. However, upon exposure to genotoxic stress, ATM phosphorylates DYRK2, leading to its dissociation from MDM2 and its phosphorylation of p53, thereby inducing apoptosis. Recent evidence also suggests that DYRK2 may serve as a scaffold that facilitates assembly of an E3 ubiquitin ligase.Synonyms: Dual specificity tyrosine-phosphorylation-regulated kinase 2
    基因ID
    8445
    NCBI登录号
    NP_003574
    UniProt
    Q92630
    途径
    Regulation of Carbohydrate Metabolic Process
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