DYRK2 抗体 (C-Term)
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Quick Overview for DYRK2 抗体 (C-Term) (ABIN783436)
抗原
See all DYRK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects DYRK2 at C-term. Two isoforms of DYRK2 are known to exist, this antibody will recognize both isoforms. DYRK2 antibody will not cross-react with other DYRK family members.
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交叉反应 （详细）
- Species reactivity (tested):Human
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 18 amino acid peptide near the carboxy terminus of human DYRK2
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anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) (AA 1-100) antibody
DYRK2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 6E2 unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) (AA 1-100) antibodyDYRK2 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2F9 unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) (AA 521-549), (C-Term) antibodyDYRK2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB34467 unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) (AA 105-135), (N-Term) antibodyDYRK2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB3008 unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) (AA 502-601) antibodyDYRK2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) (AA 1-100) antibodyDYRK2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4G11 unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) (AA 1-100) antibodyDYRK2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2F9 unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) (C-Term) antibodyDYRK2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) (C-Term) antibodyDYRK2 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) (AA 434-483) antibodyDYRK2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- DYRK2 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2))
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别名
- DYRK2
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背景
- DYRK2 is a member of the dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family that is thought to be involved in cellular proliferation and apoptosis. Under normal conditions, nuclear but not cytoplasmic DYRK2 is ubiquitinated by MDM2, leading to its constitutive degradation. However, upon exposure to genotoxic stress, ATM phosphorylates DYRK2, leading to its dissociation from MDM2 and its phosphorylation of p53, thereby inducing apoptosis. Recent evidence also suggests that DYRK2 may serve as a scaffold that facilitates assembly of an E3 ubiquitin ligase.Synonyms: Dual specificity tyrosine-phosphorylation-regulated kinase 2
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基因ID
- 8445
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NCBI登录号
- NP_003574
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UniProt
- Q92630
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途径
- Regulation of Carbohydrate Metabolic Process
抗原
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