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ESRP2 抗体 (C-Term)

The 兔 多克隆 anti-ESRP2 antibody is suitable to detect ESRP2 in samples from 人 和 小鼠. It has been validated for WB 和 EIA.
产品编号 ABIN783407
发货至: 中国
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Quick Overview for ESRP2 抗体 (C-Term) (ABIN783407)

抗原

See all ESRP2 抗体
ESRP2 (Epithelial Splicing Regulatory Protein 2 (ESRP2))

适用

  • 41
  • 35
  • 16
  • 5
  • 5
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 39
  • 3

克隆类型

  • 41
  • 1
多克隆

标记

  • 17
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ESRP2 antibody is un-conjugated

应用范围

  • 30
  • 13
  • 13
  • 13
  • 4
  • 3
  • 3
  • 2
  • 2
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 15
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term

    特异性

    This antibody detects ESRP2 / RBM35B at C-term. RBM35B antibody is predicted to not cross-react with other RBM35/ESRP family members. At least three isoforms of RBM35B are known to exist, this antibody will detect all three.

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    17 amino acid peptide near the carboxy terminus of human RBM35B
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • 抗原

    ESRP2 (Epithelial Splicing Regulatory Protein 2 (ESRP2))

    别名

    ESRP2 / RBM35B

    背景

    RBM35A, also known as ESRP2, is a mRNA splicing factor that with its related protein RBM35A (ESRP1) are coordinators of an epithelial cell-type-specific splicing program. Both RBM35B and RBM35A are involved in posttranscriptional regulation of a number of genes such as FGFR2, CD44, CTNND1, and ENAH by exerting a differential effect on protein translation via 5' UTRs of mRNAs, suggesting that these proteins are global regulators of an epithelial regulatory network. Loss of this global ESRP-regulated epithelial splicing programme induces the phenotypic changes in cell morphology that are observed during the epithelial-mesenchymal transition.Synonyms: Epithelial splicing regulatory protein 2, RNA-binding motif protein 35B, RNA-binding protein 35B

    基因ID

    80004

    NCBI登录号

    NP_079215

    UniProt

    Q9H6T0
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