PKM2 抗体 (AA 399-403)
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Quick Overview for PKM2 抗体 (AA 399-403) (ABIN783340)
抗原
See all PKM2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 399-403
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序列
- V-R-A-S-S
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特异性
- This antibody detects endogenous levels of total PKM1 protein.
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交叉反应 （详细）
- Species reactivity (tested):Human, Mouse
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纯化方法
- Affinity-chromatography using epitope-specific peptide
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免疫原
- Peptide sequence around aa. 399~403
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anti-Pyruvate Kinase M2 (PKM2) (AA 141-248) antibody
PKM2 适用: 人 WB, IHC, FACS, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 294-470) antibodyPKM2 适用: 人 WB, IHC, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase M2 (PKM2) (pTyr105) antibodyPKM2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 476-505), (C-Term) antibodyPKM2 适用: 人, 小鼠, 大鼠, 猴 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB3697 unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 383-417), (C-Term) antibodyPKM2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18405 unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 476-505) antibodyPKM2 适用: 人, 小鼠, 大鼠, 灵长类 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 116-145) antibodyPKM2 适用: 人 WB, IHC, FACS, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 255-350) antibodyPKM2 适用: 人, 小鼠, 大鼠 WB, FACS, ELISA, ICC, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase M2 (PKM2) antibodyKD Validated PKM2 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2170 unconjugated Recombinant Antibody
anti-Pyruvate Kinase M2 (PKM2) (AA 1-531) antibodyPKM2 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store (in aliquots) at -20 °C.
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- PKM2 (Pyruvate Kinase M2 (PKM2))
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别名
- PKM2
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背景
- Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio betwween the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival.Synonyms: CTHBP, Cytosolic thyroid hormone-binding protein, M2-PK, OIP-3, OIP3, Opa-interacting protein 3, PK2, PK3, PKM, Pyruvate kinase 2/3, Pyruvate kinase M1/M2, Pyruvate kinase isozymes M1/M2, Pyruvate kinase muscle, Pyruvate kinase muscle isozyme, THBP1
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分子量
- 60 kDa
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基因ID
- 5315
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NCBI登录号
- NP_002645
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UniProt
- P14618
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途径
- Warburg Effect
抗原
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