PKM2 抗体 (AA 255-350)
(2 references)-
- 抗原 See all PKM2 抗体
- PKM2 (Pyruvate Kinase M2 (PKM2))
-
抗原表位
- AA 255-350
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This PKM2 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Cow,Pig,Horse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from mouse Pyruvate kinase PKM
- 亚型
- IgG
- Top Product
- Discover our top product PKM2 Primary Antibody
-
anti-Pyruvate Kinase M2 (PKM2) (AA 294-470) antibody
PKM2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 141-248) antibodyPKM2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase M2 (PKM2) (pTyr105) antibodyPKM2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 476-505), (C-Term) antibodyPKM2 适用: 人, 小鼠, 大鼠, 猴 WB, IHC (p), IF 宿主: 兔 Polyclonal RB3697 unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 383-417), (C-Term) antibodyPKM2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18405 unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 476-505) antibodyPKM2 适用: 人, 小鼠, 大鼠, 灵长类 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 116-145) antibodyPKM2 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 1-531) antibodyPKM2 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 483-513) antibodyPKM2 适用: 人, 小鼠, 大鼠, 猴, 灵长类 WB, ELISA, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 51-150) antibodyPKM2 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), ICC, IHC (fro) 宿主: 小鼠 Polyclonal unconjugated
-
- 应用备注
-
WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
-
-
: "Differential proteome and gene expression reveal response to carbon ion irradiation in pubertal mice testes." in: Toxicology letters, Vol. 225, Issue 3, pp. 433-44, (2014) (PubMed).
: "Role of Fas-associated death domain-containing protein (FADD) phosphorylation in regulating glucose homeostasis: from proteomic discovery to physiological validation." in: Molecular & cellular proteomics : MCP, Vol. 12, Issue 10, pp. 2689-700, (2013) (PubMed).
-
: "Differential proteome and gene expression reveal response to carbon ion irradiation in pubertal mice testes." in: Toxicology letters, Vol. 225, Issue 3, pp. 433-44, (2014) (PubMed).
-
- 抗原
- PKM2 (Pyruvate Kinase M2 (PKM2))
- 别名
- PKM2 (PKM2 产品)
- 别名
- CTHBP antibody, OIP3 antibody, PK3 antibody, PKM2 antibody, TCB antibody, THBP1 antibody, AA414905 antibody, AL024370 antibody, AL024424 antibody, Pk-2 antibody, Pk-3 antibody, Pk3 antibody, Pkm2 antibody, PKM12 antibody, PKM antibody, pyruvate kinase M1/2 antibody, pyruvate kinase, muscle antibody, PKM antibody, Pkm antibody
- 背景
-
Synonyms: PK3, TCB, OIP3, PKM2, CTHBP, THBP1, HEL-S-3, Pyruvate kinase PKM, Cytosolic thyroid hormone-binding protein, Opa-interacting protein 3, OIP-3, Pyruvate kinase 2/3, Pyruvate kinase muscle isozyme, Thyroid hormone-binding protein 1, Tumor M2-PK, p58, PKM, PK2, Pyruvate kinase PKLR, Pyruvate kinase 1, R-type/L-type pyruvate kinase, Red cell/liver pyruvate kinase.
Background: Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio betwween the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival.
- 基因ID
- 5315, 5313
- UniProt
- P14618, P30613
- 途径
- Warburg Effect
-
