CR1L 抗体
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北京 101111
Quick Overview for CR1L 抗体 (ABIN782451)
抗原
See all CR1L 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Purified Anti-Rat Crry monoclonal antibody (Clone: 5I2) is a rat-specific membrane complement regulator that can inhibit both antibody-induced classical pathway and alternative pathway complement activation. Crry plays a more dominant role than DAF in regulating the alternative pathway of complement and in preventing spontaneous complement damage of rat erythrocytes, whereas DAF and Crry are both expressed and are equally effective in preventing antibody-induced runaway complement activation on rat erythrocytes.
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纯化方法
- Affinity chromatography on Protein G
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免疫原
- Erythrocytes from a C3 mutated rat
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- PBS containing 0.02 % sodium azide (NaN3) as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CR1L (Complement Component (3b/4b) Receptor 1-Like (CR1L))
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别名
- CR1L / CRRY
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背景
- Synonyms: Antigen 5I2, Complement component receptor 1-like protein, Complement regulatory protein Crry
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基因ID
- 54243
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NCBI登录号
- NP_001005265
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UniProt
- Q63135
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途径
- Complement System
抗原
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