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C3AR1 抗体 (AA 63-8)

This anti-C3AR1 antibody is a 小鼠 单克隆 antibody detecting C3AR1 in FACS 和 IHC (fro). Suitable for 大鼠.
产品编号 ABIN782447
发货至: 中国

Quick Overview for C3AR1 抗体 (AA 63-8) (ABIN782447)

抗原

See all C3AR1 抗体
C3AR1 (Complement Component 3a Receptor 1 (C3AR1))

适用

  • 47
  • 24
  • 9
大鼠

宿主

  • 39
  • 18
小鼠

克隆类型

  • 39
  • 17
  • 1
单克隆

标记

  • 28
  • 5
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This C3AR1 antibody is un-conjugated

应用范围

  • 25
  • 24
  • 13
  • 13
  • 13
  • 12
  • 8
  • 7
  • 3
  • 3
Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

74
  • 抗原表位

    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 63-8

    特异性

    This rat C3a receptor antibody detects a recombinant peptide corresponding to amino acids 161-321 of the large extracellular loop structure, which shares 34 % homology with mouse and human. Deduced amino acid sequences of human/rat C3aR is 58.5 % and 90.7 % with rat/mouse.

    纯化方法

    Affinity chromatography on Protein G

    免疫原

    RBL-2H3 transfectants expressing rat C3aR Donor: BALB/c Fusion Partner: X63-Ag8.653

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1,0 mg/mL

    缓冲液

    PBS containing 0.02 % sodium azide (NaN3) as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    C3AR1 (Complement Component 3a Receptor 1 (C3AR1))

    背景

    C3aR binds to anaphylotoxin C3a which, among other things, is involved in mast cell degranulation and recruitment of immune cells to the site of inflammation. Activation of the complement cascade produces various fragments, including C3a and C5a. C3aR is characterized by seven transmembrane domains including a large extracellular loop which is coupled to a Gi protein. C3aR expression is detected on glial cells, neurons and cells belonging to the mononuclear phagocyte system. C3aR expression was shown to moderately increase after LPS stimulation.Synonyms: AZ3B, C3AR, C3AR1, C3R1, C3a anaphylatoxin chemotactic receptor, C3a-R, HNFAG09

    基因ID

    84007

    NCBI登录号

    NP_114449

    UniProt

    O55197

    途径

    Complement System
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