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- 抗原 See all COBRA1 抗体
- COBRA1 (Cofactor of BRCA1 (COBRA1))
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适用
- 人, 小鼠, 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This COBRA1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- Specific for the ~62k COBRA1 protein in Western blots of neonatal Rat brain lysate.
- 交叉反应 （详细）
- Species reactivity (tested):Human, Mouse and Rat.
- 纯化方法
- Protein G Chromatography of Culture Supernatant.
- 免疫原
- Recombinant full length Human COBRA1 purified from E. coli.
- 克隆位点
- F7E4
- 亚型
- IgG1
- Top Product
- Discover our top product COBRA1 Primary Antibody
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anti-Cofactor of BRCA1 (COBRA1) (Center) antibody
COBRA1 适用: 人, 小鼠 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Cofactor of BRCA1 (COBRA1) (AA 8-199) antibodyCOBRA1 适用: 人 WB, ELISA, IHC, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Cofactor of BRCA1 (COBRA1) (AA 1-475) antibodyCOBRA1 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Cofactor of BRCA1 (COBRA1) (AA 1-475) antibodyCOBRA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cofactor of BRCA1 (COBRA1) antibodyCOBRA1 适用: 人 WB 宿主: 小鼠 Monoclonal F7E4 unconjugated
anti-Cofactor of BRCA1 (COBRA1) antibodyCOBRA1 适用: 人, 小鼠, 大鼠 WB 宿主: 小鼠 Monoclonal F7E4 unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS containing 0.05 % Sodium Azide as preservative.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store the antibody undiluted (in aliquots) at -20 °C.
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- 抗原
- COBRA1 (Cofactor of BRCA1 (COBRA1))
- 别名
- NELF-B (COBRA1 产品)
- 别名
- LOC100219583 antibody, COBRA1 antibody, NELF-B antibody, bZ1O1.4 antibody, cobra1 antibody, cobra2 antibody, fe01e12 antibody, wu:fe01e12 antibody, zgc:55628 antibody, MGC131073 antibody, Cobra1 antibody, RGD1307832 antibody, A730008L03Rik antibody, AB041607 antibody, AI663983 antibody, Nelf-b antibody, cofactor of BRCA1 antibody, negative elongation factor complex member B antibody, negative elongation factor complex member B L homeolog antibody, LOC100219583 antibody, NELFB antibody, nelfb antibody, nelfb.L antibody, Nelfb antibody
- 背景
- COBRA1 (cofactor of BRCA1) also known as NELF-B, is an essential component of the negative elongation factor (NELF) complex. COBRA1 has been shown to directly bind estrogen receptor alpha (ERα) and repress ERα-mediated transcription (Aiyar SE et al., 2004). COBRA1 has also been demonstrated to interact with c-Jun and c-Fos suggesting a role in modulation of the AP-1 pathway and therefore may be important in cell proliferation, differentiation, apoptosis and oncogeneis (Zhong H et al., 2004).Synonyms: COBRA1, Cofactor of BRCA1, KIAA1182, NELFB, Negative elongation factor B
- 基因ID
- 25920
- NCBI登录号
- NP_056271
- UniProt
- Q8WX92
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