SMAD3 抗体
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Quick Overview for SMAD3 抗体 (ABIN781908)
抗原
See all SMAD3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody reacts to SMAD3.
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交叉反应 (详细)
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Species reactivity (expected):Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography on Protein A
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免疫原
- SMAD3 antibody was raised against recombinant protein
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0,43 mg/mL
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缓冲液
- PBS, pH 7.2
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- SMAD3 (SMAD, Mothers Against DPP Homolog 3 (SMAD3))
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别名
- SMAD3
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背景
- SMAD3, a transcriptional regulator, is activated by TGF-beta and Activin 1 receptor kinase. SMAD3 recognizes an 8 bp palindromic sequence GTCTAGAC. Upon phosphorylation at two extreme C-terminal serines, SMAD3 is translocated into the nucleus where is forms complexes other SMAD proteins, depending on the activation pathway, and regulates the transcription of target genes.Synonyms: JV15-2, MAD homolog 3, MAD-3, MADH3, Mad3, Mothers against DPP homolog 3, Mothers against decapentaplegic homolog 3, SMAD 3, SMAD family member 3, SMAD-3
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基因ID
- 4088
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NCBI登录号
- NP_001138574
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UniProt
- P84022
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途径
- Cell Division Cycle, Chromatin Binding, Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity, Autophagy
抗原
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