ESR2 抗体 (AA 512-530)
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- 抗原 See all ESR2 抗体
- ESR2 (Estrogen Receptor 2 (ESR2))
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抗原表位
- AA 512-530
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适用
- 人, 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This ESR2 antibody is un-conjugated
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应用范围
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 特异性
- Monoclonal antibody 4ERβ-2D7 recognizes an epitope in the F region of the mouse and human Estrogen Receptor beta. The two different forms of the estrogen receptor, usually referred to as α and β, can form hormone-activated dimers, and, since the two forms are coexpressed in many cell types, the receptors may form ERα (αα) or ERβ (ββ) homodimers or ERαβ (αβ) heterodimers. Estrogen receptor alpha and beta show significant overall sequence homology, and both are composed of five domains (A-F domains listed from the N- to C-terminus). Antigen distribution: The antigen has been described in kidney, brain, bone, heart, lungs, intestinal mucosa, prostate, and endothelial cells. No cross-reactivity has been observedwith ER-alpha
- 交叉反应 （详细）
- Species reactivity (tested):Human and Mouse.
- 纯化方法
- Affinity Chromatography
- 免疫原
- Peptide C512 to Q530 from murine ERbeta. Antigen: Estrogen Receptor beta. Epitope: Located in the F region.
- 克隆位点
- ERbeta-2D7
- 亚型
- IgG1
- Top Product
- Discover our top product ESR2 Primary Antibody
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anti-Estrogen Receptor 2 (ESR2) (C-Term) antibody
ESR2 适用: 人, 小鼠, 大鼠, 绵羊, Pig, 马, 猴 WB, IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal ERb455 unconjugated
anti-Estrogen Receptor 2 (ESR2) (N-Term) antibodyESR2 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Estrogen Receptor 2 (ESR2) (C-Term) antibodyESR2 适用: 人, 小鼠, 大鼠, 绵羊, Pig, 马, 猴 WB, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal ERb455 unconjugated
anti-Estrogen Receptor 2 (ESR2) (AA 201-300) antibodyESR2 适用: 人, 小鼠, 大鼠, 绵羊 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Estrogen Receptor 2 (ESR2) (AA 50-100) antibodyESR2 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Estrogen Receptor 2 (ESR2) (AA 46-530) antibodyESR2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Estrogen Receptor 2 (ESR2) (pSer105) antibodyESR2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Estrogen Receptor 2 (ESR2) (AA 211-240) antibodyESR2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB41114 unconjugated
anti-Estrogen Receptor 2 (ESR2) (AA 22-121) antibodyESR2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3F3 unconjugated
anti-Estrogen Receptor 2 (ESR2) (C-Term) antibodyESR2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IP 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 溶解方式
- Restore by adding 0.5 mL distilled water
- 浓度
- 0.5 mg/mL
- 缓冲液
- Stock solution contains 0.5 mg/mL IgG, PBS, pH 7.2 with 5 mg/mL BSA as stabilizer and 0.01 % Kathon as a preservative.
- 储存液
- Kathon CG
- 注意事项
- This product contains Kathon CG a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the lyophilized antibody at 2- 8 °C. Following reconstitution, store at -20 °C.
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- 抗原
- ESR2 (Estrogen Receptor 2 (ESR2))
- 别名
- Estrogen Receptor beta (ESR2 产品)
- 别名
- ER-BETA antibody, ESR-BETA antibody, ESRB antibody, ESTRB antibody, Erb antibody, NR3A2 antibody, ER[b]1 antibody, zfER-beta1 antibody, zfER[b]1 antibody, erb2 antibody, CERB antibody, ERB antibody, erb antibody, esrb antibody, estrb antibody, nr3a2 antibody, ERbeta antibody, er-beta antibody, esr-beta antibody, ESR2 antibody, ERBETA antibody, er antibody, ER-beta antibody, ER[b] antibody, Estrb antibody, ER[b]2 antibody, ER[b]a antibody, zfER[b]2 antibody, zfER-beta2 antibody, Erb2 antibody, esr2 antibody, erbeta antibody, Esr2 antibody, ERBeta2 antibody, estrogen receptor 2 antibody, estrogen receptor 2b antibody, estrogen receptor beta 2 antibody, estrogen receptor 2 (beta) antibody, estrogen receptor 2a antibody, estrogen receptor beta antibody, ESR2 antibody, esr2b antibody, erb2 antibody, esr2 antibody, Esr2 antibody, esr2a antibody, erbeta antibody
- 背景
- ER exists in two types: alpha and Beta. They are similar in structure. The ligand binding domain and the DNA binding domain are highly conserved in these proteins while the N-terminal transactivating domain is diverged considerably. Five isoforms of the hER beta gene, designated hER beta 1-5 have been identified. ERBeta binds to estrogen and activates genes through direct interaction with estrogen specific gene elements (ERE's). ER-Beta RNA has been detected in human thymus, spleen, ovary and testis and in rat ovary and prostrate. This tissue distribution overlaps but is not identical to that of ER - alphaRNA.Synonyms: ER-beta, ESR2, ESTRB, NR3A2, Nuclear receptor subfamily 3 group A member 2
- 基因ID
- 2100
- NCBI登录号
- NP_001035365
- UniProt
- Q92731
- 途径
- Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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