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ESR2 抗体 (C-Term)

ESR2 适用: 人, 小鼠, 大鼠, 绵羊, Pig, 马, 猴 WB, IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal ERb455 unconjugated
产品编号 ABIN6939350
发货至: 中国
  • 抗原 See all ESR2 抗体
    ESR2 (Estrogen Receptor 2 (ESR2))
    抗原表位
    • 27
    • 18
    • 16
    • 16
    • 13
    • 8
    • 8
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    • 6
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    C-Term
    适用
    • 190
    • 112
    • 93
    • 31
    • 18
    • 15
    • 14
    • 7
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    • 5
    • 4
    • 3
    • 2
    人, 小鼠, 大鼠, 绵羊, Pig, 马, 猴
    宿主
    • 168
    • 35
    • 1
    • 1
    小鼠
    克隆类型
    • 161
    • 44
    单克隆
    标记
    • 93
    • 18
    • 15
    • 9
    • 8
    • 5
    • 5
    • 5
    • 5
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    • 5
    • 5
    • 3
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    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ESR2 antibody is un-conjugated
    应用范围
    • 171
    • 76
    • 54
    • 38
    • 37
    • 26
    • 26
    • 19
    • 11
    • 11
    • 10
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    • 4
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    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Staining Methods (StM)
    纯化方法
    Purified by Protein A/G
    免疫原
    C-terminus fragment of recombinant human estrogen receptor beta protein
    克隆位点
    ERb455
    亚型
    IgG2a kappa
  • 应用备注

    Positive Control: MCF-7 cells. Ovarian, Breast, Bladder, Gastric or Salivary carcinoma.

    Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Western Blot (0.5-1 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT) (Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    ESR2 (Estrogen Receptor 2 (ESR2))
    别名
    ESR2 (ESR2 产品)
    别名
    ER-BETA antibody, ESR-BETA antibody, ESRB antibody, ESTRB antibody, Erb antibody, NR3A2 antibody, ER[b]1 antibody, zfER-beta1 antibody, zfER[b]1 antibody, erb2 antibody, CERB antibody, ERB antibody, erb antibody, esrb antibody, estrb antibody, nr3a2 antibody, ERbeta antibody, er-beta antibody, esr-beta antibody, ESR2 antibody, ERBETA antibody, er antibody, ER-beta antibody, ER[b] antibody, Estrb antibody, ER[b]2 antibody, ER[b]a antibody, zfER[b]2 antibody, zfER-beta2 antibody, Erb2 antibody, esr2 antibody, erbeta antibody, Esr2 antibody, ERBeta2 antibody, estrogen receptor 2 antibody, estrogen receptor 2b antibody, estrogen receptor beta 2 antibody, estrogen receptor 2 (beta) antibody, estrogen receptor 2a antibody, estrogen receptor beta antibody, ESR2 antibody, esr2b antibody, erb2 antibody, esr2 antibody, Esr2 antibody, esr2a antibody, erbeta antibody
    背景
    Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including ER-alpha and ER-beta, contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. They are located in the nucleus, though some estrogen receptors associate with the cell surface membrane and can be rapidly activated by exposure of cells to estrogen. ER-alpha and ER-beta are differentially activated by various ligands. Receptor-ligand interactions trigger a cascade of events, including dissociation from heat shock proteins, receptor dimerization, phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes. Evidence suggests that ER-alpha and ER-beta may be regulated by distinct mechanisms even though they share many functional characteristics.
    分子量
    53-59kDa
    基因ID
    2100
    UniProt
    Q92731
    途径
    Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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