MAP2 抗体
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北京 101111
Quick Overview for MAP2 抗体 (ABIN781313)
抗原
See all MAP2 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Cytoplasm
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纯化方法
- Protein G-Sepharose affinity purified.
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免疫原
- Recombinant fragment of Human MAP2 (C-terminus).
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亚型
- IgG
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应用备注
- Recommended dilutions. ELISA: 1/5000 - 1/20000. WB: 1/100-1/2000.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 50µg/50µl
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缓冲液
- 0.02% Sodium Azide and 50% glycerol, 1% BSA, PBS, pH7.4.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- MAP2 (Microtubule-Associated Protein 2 (MAP2))
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别名
- MAP2
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背景
- Microtubule-associated protein 2 (MAP2) is a neuronal phosphoprotein that regulates the structure and stability of microtubules, neuronal morphogenesis, cytoskeleton dynamics and organelle trafficking in axons and dendrites. Phosphorylation of MAP2 modulates its association with the cytoskeleton and is developmentally regulated. Serine 136, threonine 1620 and threonine 1623 of MAP2 are phosphorylated by GSK3 and p44/42 MAP kinases. Phosphorylation at threonine 1620/1623 by GSK3 inhibits MAP2 association with microtubules and microtubule stability.
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分子量
- 50kDa
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NCBI登录号
- NM_031846
抗原
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