Complement C3c 抗体
Quick Overview for Complement C3c 抗体 (ABIN768895)
抗原
适用
宿主
克隆类型
标记
应用范围
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品牌
- IHC-plus™
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特异性
- Detects human complement 3c, a polypeptide fragment which is present in C3. C3 plays a central role in the activation of the complement system. Processing of C3 by C3 convertase is the central reaction in both classical and alternative complement pathways, resulting in C3a and C3b. C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates, and help to initiate the complement cascade, potentially resulting in cellular apoptosis. C3a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. C3b is rapidly split in two positions by factor I and a cofactor to form iC3b (inactivated C3b) and C3f which is released. Then iC3b is slowly cleaved (possibly by factor I) to form C3c and C3dg. Defects in C3 can result in susceptibility to pyogenic infection. Shows minimal reactivity with related serum proteins.
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纯化方法
- Protein G purified
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免疫原
- Native human C3 / Complement C3.
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亚型
- IgG
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anti-Complement Component C3c (C3C) (AA 1521-1649) antibody
C3C 适用: 人 ELISA, WB, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 4C6A8 unconjugated
anti-Complement Component C3c (C3C) (AA 1521-1649) antibodyC3C 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 8B5H2 unconjugated
anti-Complement Component C3c (C3C) antibodyC3C 适用: 人 IHC (p), ID 宿主: 山羊 Polyclonal unconjugated
anti-Complement Component C3c (C3C) antibodyC3C 适用: 人 IHC (p), ID 宿主: 兔 Polyclonal unconjugated
anti-Complement Component C3c (C3C) (AA 1051-1200) antibodyC3C 适用: 人, 大鼠, Pig ELISA, WB, ICC, IF (p), IF (cc), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Approved: ELISA (1:400), IHC, IHC-Fr (1:50), IHC-P (5 μg/mL)
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说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- avoid freeze thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
- Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.
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- Complement C3c (C3C) (Complement Component C3c (C3C))
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别名
- Complement C3/C3c
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UniProt
- P01024
抗原
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