VAV2 抗体 (AA 401-500)
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- 抗原 See all VAV2 抗体
- VAV2 (Vav 2 Guanine Nucleotide Exchange Factor (VAV2))
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抗原表位
- AA 401-500
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This VAV2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Pig
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human VAV2
- 亚型
- IgG
- Top Product
- Discover our top product VAV2 Primary Antibody
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anti-Vav 2 Guanine Nucleotide Exchange Factor (VAV2) (AA 552-868) antibody
VAV2 适用: 人 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 3F5D3 unconjugated
anti-Vav 2 Guanine Nucleotide Exchange Factor (VAV2) antibodyVAV2 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Vav 2 Guanine Nucleotide Exchange Factor (VAV2) antibodyVAV2 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB56694 unconjugated
anti-Vav 2 Guanine Nucleotide Exchange Factor (VAV2) (Internal Region) antibodyVerified VAV2 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Vav 2 Guanine Nucleotide Exchange Factor (VAV2) (AA 108-157), (pTyr142) antibodyVAV2 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Vav 2 Guanine Nucleotide Exchange Factor (VAV2) antibodyVAV2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Vav 2 Guanine Nucleotide Exchange Factor (VAV2) antibodyVAV2 适用: 人 宿主: 绵羊 Polyclonal unconjugated
anti-Vav 2 Guanine Nucleotide Exchange Factor (VAV2) (AA 612-691) antibodyVAV2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Vav 2 Guanine Nucleotide Exchange Factor (VAV2) antibodyVAV2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Vav 2 Guanine Nucleotide Exchange Factor (VAV2) (Tyr299) antibodyVAV2 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- VAV2 (Vav 2 Guanine Nucleotide Exchange Factor (VAV2))
- 别名
- Vav2 (VAV2 产品)
- 别名
- VAV-2 antibody, 2810040F13Rik antibody, AI847175 antibody, vav guanine nucleotide exchange factor 2 antibody, vav 2 oncogene antibody, VAV2 antibody, Vav2 antibody
- 背景
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Synonyms: Oncogene VAV2, Protein vav 2, VAV 2, Vav 2 oncogene, VAV2 oncogene, VAV2_HUMAN.
Background: VAV2 is a ubiquitously expressed structural homolog of the VAV protooncogene that is expressed preferentially in hematopoetic cells. Both proteins are comprised of a Dbl homology (DH) domain with guanosine nucleotide exchange (GEF) activity exclusively directed towards Rho/Rac GTPases, a pleckstrin homology (PH) domain, a calponin-homology (CH) region, an acidic domain (AD) a zinc finger butterfly motif, two SH3 regions and one SH2 domain. GEF activity of RhoA family G proteins is induced by tyrosine phosphorylation in wild type VAV2, and is constitutively activated in N terminus deleted oncogene forms. Constitutive expression of a VAV2 oncoprotein may result in morphological alterations including highly enlarged cells in which karyokinesis and cytokinesis frequently are uncoupled.
- 基因ID
- 7410
- 途径
- Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway
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