RIN1 抗体 (AA 201-300) (Cy5.5)
Quick Overview for RIN1 抗体 (AA 201-300) (Cy5.5) (ABIN762346)
抗原
See all RIN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 201-300
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交叉反应
- 大鼠
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预测反应
- Human,Mouse,Cow,Pig
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human RIN1
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- RIN1 (Ras and Rab Interactor 1 (RIN1))
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别名
- RIN1
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背景
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Synonyms: Ras and Rab interactor 1, ras inhibitor 1, ras inhibitor, RIN1_HUMAN, Ras inhibitor JC99, ras inhibitor RIN1, Ras interaction/interference protein 1, RIN 1.
Background: RIN1 is a Ras effector protein which can affect Ras signaling in a variety of ways. It enhances signaling from ABL1 and ABL2 whcih are involved in regulation of cytoskeletal remodeling. It may function as a guanine nucleotide exchange factor in activation of Rab5a. Rin1 also competes with RAF1 for binding of the activated form of Ras. It may play a role inhibiting the modulation of neuronal plasticity in formation of aversive memory, and has been implicated as a tumor supressor gene in breast cancer.
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基因ID
- 9610
抗原
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