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ZBTB33 抗体 (AA 100-180)

The 兔 多克隆 anti-ZBTB33 antibody is suitable to detect ZBTB33 in samples from 人 和 小鼠. It has been validated for WB 和 ELISA.
产品编号 ABIN8125797
发货至: 中国
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Room 801-803
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Quick Overview for ZBTB33 抗体 (AA 100-180) (ABIN8125797)

抗原

See all ZBTB33 抗体
ZBTB33 (Zinc Finger and BTB Domain Containing 33 (ZBTB33))

适用

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人, 小鼠

宿主

  • 26
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兔

克隆类型

  • 22
  • 8
多克隆

标记

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This ZBTB33 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 100-180

    原理

    KAISO Antibody

    特异性

    KAISO Polyclonal Antibody detects endogenous levels of protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from human protein . at AA range: 100-180

    亚型

    IgG
  • 应用备注

    WB 1:500-2000 ELISA 1:5000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    ZBTB33 (Zinc Finger and BTB Domain Containing 33 (ZBTB33))

    别名

    KAISO

    背景

    Background: This gene encodes a transcriptional regulator with bimodal DNA-binding specificity, which binds to methylated CGCG and also to the non-methylated consensus KAISO-binding site TCCTGCNA. The protein contains an N-terminal POZ/BTB domain and 3 C-terminal zinc finger motifs. It recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. It may contribute to the repression of target genes of the Wnt signaling pathway, and may also activate transcription of a subset of target genes by the recruitment of catenin delta-2 (CTNND2). Its interaction with catenin delta-1 (CTNND1) inhibits binding to both methylated and non-methylated DNA. It also interacts directly with the nuclear import receptor Importin-α2 (also known as karyopherin alpha2 or RAG cohort 1), which may mediate nuclear impor

    Gene Name: ZBTB33 KAISO ZNF348

    Protein Name: Transcriptional regulator Kaiso (Zinc finger and BTB domain-containing protein 33)

    基因ID

    10009

    UniProt

    Q86T24
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