XBP1 抗体
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北京 101111
Quick Overview for XBP1 抗体 (ABIN8125764)
抗原
See all XBP1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- XBP1 Rabbit mAb
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特异性
- This antibody detects endogenous levels of XBP1 protein.
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纯化方法
- The antibody was purified by protein A affinity chromatography.
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免疫原
- Recombinant protein (or fragment).
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亚型
- IgG
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anti-X-Box Binding Protein 1 (XBP1) antibody
XBP1 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-X-Box Binding Protein 1 (XBP1) (AA 51-150) antibodyXBP1 适用: 人 WB, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-X-Box Binding Protein 1 (XBP1) (Internal Region) antibodyVerified XBP1 适用: 人 WB, ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated
anti-X-Box Binding Protein 1 (XBP1) (AA 62-91) antibodyXBP1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21824 unconjugated
anti-X-Box Binding Protein 1 (XBP1) (AA 62-91) antibodyXBP1 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-X-Box Binding Protein 1 (XBP1) (N-Term) antibodyXBP1 适用: 人, 小鼠, 大鼠 WB, IHC, FACS, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-X-Box Binding Protein 1 (XBP1) (AA 1-167) antibodyXBP1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-X-Box Binding Protein 1 (XBP1) antibodyXBP1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-X-Box Binding Protein 1 (XBP1) (AA 123-225) antibodyXBP1 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 3F5 unconjugated
anti-X-Box Binding Protein 1 (XBP1) (AA 217-244), (C-Term) antibodyXBP1 适用: 小鼠 WB 宿主: 兔 Polyclonal RB31994 unconjugated
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应用备注
- WB, 1:1000-1:5000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
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- XBP1 (X-Box Binding Protein 1 (XBP1))
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别名
- XBP1
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背景
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Synonyms: XBP1, TREB5, XBP2, X-box-binding protein 1, XBP-1, Tax-responsive element-binding protein 5
Background: This gene encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box. This gene product is a bZIP protein, which was also identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter. It may increase expression of viral proteins by acting as the DNA binding partner of a viral transactivator. It has been found that upon accumulation of unfolded proteins in the endoplasmic reticulum (ER) , the mRNA of this gene is processed to an active form by an unconventional splicing mechanism that is mediated by the endonuclease inositol-requiring enzyme 1 (IRE1) . The resulting loss of 26 nt from the spliced mRNA causes a frame-shift and an isoform XBP1 (S) , which is the functionally active transcription factor. The isoform encoded by the unspliced mRNA, XBP1 (U) , is constitutively e
Gene Name: >>Protein processing in endoplasmic reticulum, >>Non-alcoholic fatty liver disease, >>Alzheimer disease, >>Parkinson disease, >>Amyotrophic lateral sclerosis, >>Spinocerebellar ataxia, >>Pathways of neurodegeneration-multiple diseases, >>Lipid and atherosclerosis
Protein Name: XBP1
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基因ID
- 7494
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UniProt
- P17861
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途径
- ER-Nucleus Signaling, Unfolded Protein Response
抗原
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