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VAV3 抗体 (pTyr173)

The 兔 多克隆 anti-VAV3 antibody is suitable to detect VAV3 in samples from 人 和 小鼠. It has been validated for WB, ELISA, IHC 和 IF.
产品编号 ABIN8125686
发货至: 中国
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Quick Overview for VAV3 抗体 (pTyr173) (ABIN8125686)

抗原

See all VAV3 抗体
VAV3 (Vav 3 Oncogene (VAV3))

适用

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  • 1
人, 小鼠

宿主

  • 88
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兔

克隆类型

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  • 12
多克隆

标记

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This VAV3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    pTyr173

    原理

    Vav3 (phospho Tyr173) Antibody

    特异性

    Phospho-Vav3 (Y173) Polyclonal Antibody detects endogenous levels of Vav3 protein only when phosphorylated at Y173.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized phospho-peptide around the phosphorylation site of human Vav3 (phospho Tyr173)

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    VAV3 (Vav 3 Oncogene (VAV3))

    别名

    Vav3

    背景

    Synonyms: VAV3, Guanine nucleotide exchange factor VAV3, VAV-3

    Background: This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008],

    Gene Name: VAV3

    Protein Name: Guanine nucleotide exchange factor VAV3

    基因ID

    10451

    UniProt

    Q9UKW4

    途径

    Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway
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