VAV3 抗体 (pTyr173)
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北京 101111
Quick Overview for VAV3 抗体 (pTyr173) (ABIN8125686)
抗原
See all VAV3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr173
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原理
- Vav3 (phospho Tyr173) Antibody
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特异性
- Phospho-Vav3 (Y173) Polyclonal Antibody detects endogenous levels of Vav3 protein only when phosphorylated at Y173.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized phospho-peptide around the phosphorylation site of human Vav3 (phospho Tyr173)
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- VAV3 (Vav 3 Oncogene (VAV3))
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别名
- Vav3
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背景
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Synonyms: VAV3, Guanine nucleotide exchange factor VAV3, VAV-3
Background: This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008],
Gene Name: VAV3
Protein Name: Guanine nucleotide exchange factor VAV3
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基因ID
- 10451
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UniProt
- Q9UKW4
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途径
- Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway
抗原
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