ULK1 抗体 (pSer757)
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北京 101111
Quick Overview for ULK1 抗体 (pSer757) (ABIN8125603)
抗原
See all ULK1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- pSer757
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原理
- ULK1 (Phospho Ser757) Rabbit mAb
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特异性
- The antibody detects endogenous levels of ULK1 protein only when phosphorylated at Ser757. The antibody does not cross-react with ULK1 phosphorylated at other sites.
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纯化方法
- The antibody was purified by protein A affinity chromatography.
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免疫原
- Recombinant protein (or fragment).
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亚型
- IgG
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应用备注
- WB, 1:2000-1:10000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
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- ULK1 (Unc-51 Like Kinase 1 (ULK1))
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别名
- ULK1
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背景
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Synonyms: ULK1, KIAA0722, Serine/threonine-protein kinase ULK1, Autophagy-related protein 1 homolog, ATG1, hATG1, Unc-51-like kinase 1
Background: catalytic activity:ATP + a protein = ADP + a phosphoprotein. , function:Involved in axon growth. Plays an essential role in neurite extension of cerebellar granule cells. , similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily. , similarity:Contains 1 protein kinase domain. , subunit:Interacts with GABARAP and GABARAPL2. , tissue specificity:Ubiquitously expressed. Detected in the following adult tissues: skeletal muscle, heart, pancreas, brain, placenta, liver, kidney, and lung. ,
Gene Name: ULK1
Protein Name: ULK1 (Phospho Ser757)
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基因ID
- 8408
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UniProt
- O75385
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途径
- Regulation of Cell Size, Autophagy
抗原
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