TYRO3 抗体 (pTyr685, pTyr753)
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北京 101111
Quick Overview for TYRO3 抗体 (pTyr685, pTyr753) (ABIN8125492)
抗原
See all TYRO3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr685, pTyr753
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原理
- MER/TYRO3 (Phospho Tyr753/Tyr685) Antibody
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特异性
- This antibody detects endogenous levels of MER/TYRO3 at Human:Y753/Y685,Mouse:Y748/Y675,Rat:Y748/Y675, It doesn't reacte with total protein.
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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免疫原
- Synthesized phospho-peptide around the phosphorylation site of human MER/TYRO3 (Phospho-Tyr753/Tyr685)
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亚型
- IgG
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应用备注
- WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, containing 0.02 % sodium azide as Preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- TYRO3 (TYRO3 Protein Tyrosine Kinase (TYRO3))
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别名
- MER/TYRO3
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背景
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Synonyms: MERTK MER
Background: This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). [provided by RefSeq, Jul 2008],
Gene Name: MERTK MER
Protein Name: c-mer proto-oncogene tyrosine kinase
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基因ID
- 10461
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UniProt
- Q12866
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途径
- RTK signaling
抗原
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