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Tropomyosin 抗体 (AA 101-150)

The 兔 多克隆 anti-Tropomyosin antibody is suitable to detect Tropomyosin in samples from 人, 大鼠 和 小鼠. It has been validated for WB 和 ELISA.
产品编号 ABIN8125407
发货至: 中国
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Quick Overview for Tropomyosin 抗体 (AA 101-150) (ABIN8125407)

抗原

See all Tropomyosin (TPM1) 抗体
Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))

适用

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人, 大鼠, 小鼠

宿主

  • 66
  • 22
兔

克隆类型

  • 45
  • 43
多克隆

标记

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This Tropomyosin antibody is un-conjugated

应用范围

  • 54
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Western Blotting (WB), ELISA
  • 抗原表位

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    • 1
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    AA 101-150

    原理

    Tropomyosin α Antibody

    特异性

    Tropomyosin α Polyclonal Antibody detects endogenous levels of Tropomyosin α

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from human Tropomyosin alpha. at AA range: 101-150

    亚型

    IgG
  • 应用备注

    WB 1:500-2000, ELISA 1:10000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))

    别名

    Tropomyosin alpha

    背景

    Synonyms: Tropomyosin alpha-1 chain (Alpha-tropomyosin) (Tropomyosin-1)

    Background: This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy. [provided by

    Gene Name: TPM1

    Protein Name: Tropomyosin α

    基因ID

    7168

    UniProt

    P09493

    途径

    Regulation of Actin Filament Polymerization
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