Tropomyosin 抗体 (AA 101-150)
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北京 101111
Quick Overview for Tropomyosin 抗体 (AA 101-150) (ABIN8125407)
抗原
See all Tropomyosin (TPM1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 101-150
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原理
- Tropomyosin α Antibody
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特异性
- Tropomyosin α Polyclonal Antibody detects endogenous levels of Tropomyosin α
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human Tropomyosin alpha. at AA range: 101-150
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亚型
- IgG
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应用备注
- WB 1:500-2000, ELISA 1:10000-20000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))
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别名
- Tropomyosin alpha
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背景
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Synonyms: Tropomyosin alpha-1 chain (Alpha-tropomyosin) (Tropomyosin-1)
Background: This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy. [provided by
Gene Name: TPM1
Protein Name: Tropomyosin α
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基因ID
- 7168
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UniProt
- P09493
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途径
- Regulation of Actin Filament Polymerization
抗原
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