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Topoisomerase I 抗体

This 兔 多克隆 antibody specifically detects Topoisomerase I in WB 和 ELISA. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN8125244
发货至: 中国
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Quick Overview for Topoisomerase I 抗体 (ABIN8125244)

抗原

See all Topoisomerase I (TOP1) 抗体
Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))

适用

  • 94
  • 52
  • 30
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 77
  • 15
  • 2
兔

克隆类型

  • 54
  • 40
多克隆

标记

  • 48
  • 8
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Topoisomerase I antibody is un-conjugated

应用范围

  • 67
  • 38
  • 27
  • 27
  • 23
  • 20
  • 8
  • 7
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 原理

    Topo I Antibody

    特异性

    Topo I Polyclonal Antibody detects endogenous levels of Topo I protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from the Internal region of human Topo I.

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))

    别名

    Topo I

    背景

    Synonyms: TOP1, DNA topoisomerase 1, DNA topoisomerase I

    Background: This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22. [provided by RefSeq, Jul 2008],

    Gene Name: TOP1

    Protein Name: DNA topoisomerase 1

    基因ID

    7150

    UniProt

    P11387

    途径

    Caspase Cascade in Apoptosis, Stem Cell Maintenance
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