Topoisomerase I 抗体 (N-Term)
(2 references)-
- 抗原 See all Topoisomerase I (TOP1) 抗体
- Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Topoisomerase I antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS)
- 纯化方法
- This antibody is purified through a protein G column, followed by dialysis against PBS.
- 免疫原
- This TOP1 antibody is generated from a mouse immunized with a recombinant protein from the N-terminal region of human TOP1.
- 克隆位点
- 1291CT875-142-166
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product TOP1 Primary Antibody
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anti-Topoisomerase (DNA) I (TOP1) (AA 692-765) antibody
TOP1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1A1 unconjugated
anti-Topoisomerase (DNA) I (TOP1) antibodyTOP1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Topoisomerase (DNA) I (TOP1) antibodyTOP1 适用: 人 WB, ELISA, IHC, IP, FACS 宿主: 兔 Monoclonal 6D8 unconjugated Recombinant Antibody
anti-Topoisomerase (DNA) I (TOP1) antibodyTOP1 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) I (TOP1) (Internal Region) antibodyTOP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) I (TOP1) (AA 1-100) antibodyTOP1 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) I (TOP1) antibodyTOP1 适用: 人, 大鼠 WB, FACS 宿主: 小鼠 Monoclonal 1C6 unconjugated
anti-Topoisomerase (DNA) I (TOP1) (AA 358-501) antibodyTOP1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) I (TOP1) (AA 692-765) antibodyTOP1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Topoisomerase (DNA) I (TOP1) (AA 50-99) antibodyTOP1 适用: 人, 小鼠, 大鼠, 兔, Cow, 豚鼠, 马, Pig, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000. FC: 1:25
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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- 抗原
- Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))
- 别名
- TOP1 (TOP1 产品)
- 别名
- CG6146 antibody, Dmel\\CG6146 antibody, TOP1 antibody, TopI antibody, Topo I antibody, TopoI antibody, dTopoI antibody, l(1)G0134 antibody, l(1)G0201 antibody, l(1)G0229 antibody, l(1)G0278 antibody, l(1)top1 antibody, top1 antibody, topo I antibody, topoI antibody, DNA topoisomerase 1 beta antibody, DNA topoisomerase I alpha antibody, MGO1 antibody, MGOUN 1 antibody, MTE17.1 antibody, MTE17_1 antibody, TOP1BETA antibody, TOPOISOMERASE 1 antibody, TOPI antibody, AI467334 antibody, D130064I21Rik antibody, Top-1 antibody, Ab2-086 antibody, topi antibody, Topoisomerase 1 antibody, DNA topoisomerase I antibody, DNA topoisomerase I alpha antibody, DNA topoisomerase 1 antibody, topoisomerase (DNA) I antibody, DNA topoisomerase I, gene 1 L homeolog antibody, Top1 antibody, top1 antibody, topA antibody, ZMO1193 antibody, MRAD2831_RS63095 antibody, Lferr_0016 antibody, PC1_2015 antibody, Za10_0136 antibody, Gbro_0575 antibody, Dd586_2108 antibody, Kvar_3044 antibody, Alvin_2069 antibody, Dacet_0849 antibody, Mrub_1615 antibody, Arnit_2962 antibody, Ndas_4953 antibody, Trad_2377 antibody, Acear_1653 antibody, Mahau_0844 antibody, Mesop_4109 antibody, Thein_1586 antibody, Theth_0241 antibody, TOP1ALPHA antibody, top-1 antibody, TOP1 antibody, top1.1.L antibody
- 物质类
- Viral Protein
- 背景
- Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity). Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells.
- 分子量
- 90726
- UniProt
- P11387
- 途径
- Caspase Cascade in Apoptosis, Stem Cell Maintenance
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