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TBK1 抗体

The 兔 单克隆 anti-TBK1 antibody is suitable to detect TBK1 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, ELISA, IHC, IF 和 IP.
产品编号 ABIN8125110
发货至: 中国
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Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for TBK1 抗体 (ABIN8125110)

抗原

See all TBK1 抗体
TBK1 (TANK-Binding Kinase 1 (TBK1))

适用

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人, 小鼠, 大鼠

宿主

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兔

克隆类型

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单克隆

标记

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This TBK1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

克隆位点

AB1981
  • 原理

    TBK1 Rabbit mAb

    特异性

    This antibody detects endogenous levels of TBK1 protein.

    纯化方法

    The antibody was purified by protein A affinity chromatography.

    免疫原

    Recombinant protein (or fragment).

    亚型

    IgG
  • 应用备注

    WB, 1:2000-1:10000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at-20°C. Avoid freeze / thaw cycles.
  • 抗原

    TBK1 (TANK-Binding Kinase 1 (TBK1))

    别名

    TBK1

    背景

    Synonyms: TBK1, NAK, Serine/threonine-protein kinase TBK1, NF-kappa-B-activating kinase, T2K, TANK-binding kinase 1

    Background: The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. [provided by RefSeq, Oct 2010],

    Gene Name: TBK1

    Protein Name: TBK1

    基因ID

    29110

    UniProt

    Q9UHD2

    途径

    TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interactome
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