T-Bet 抗体
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北京 101111
Quick Overview for T-Bet 抗体 (ABIN8125078)
抗原
See all T-Bet 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- T-bet mouse mAb
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特异性
- This antibody detects endogenous levels of T-bet protein.
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纯化方法
- The antibody was purified by protein G affinity chromatography.
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免疫原
- A synthetic peptide corresponding to the amino acid region 100-200 of the human T-bet protein.
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亚型
- IgG
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应用备注
- WB, 1:500-1:2000 | IF, 1:100-400 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
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- T-Bet
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背景
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Synonyms: T-box transcription factor TBX21 (T-box protein 21) (T-cell-specific T-box transcription factor T-bet) (Transcription factor TBLYM)
Background: T-box 21(TBX21) Homo sapiens This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells. [provided by RefSeq, Jul 2008],
Gene Name: TBX21
Protein Name: T-bet
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基因ID
- 30009
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UniProt
- Q9UL17
抗原
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