SMC1A 抗体 (pSer360)
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北京 101111
Quick Overview for SMC1A 抗体 (pSer360) (ABIN8124994)
抗原
See all SMC1A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer360
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原理
- SMC1 (Phospho Ser360) Antibody
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特异性
- This antibody detects endogenous levels of Human Mouse Rat SMC1 (phospho-Ser360)
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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免疫原
- Synthesized phosho peptide around human SMC1 (Ser360)
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亚型
- IgG
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应用备注
- WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- SMC1A (Structural Maintenance of Chromosomes 1A (SMC1A))
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别名
- SMC1
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背景
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Synonyms: Structural maintenance of chromosomes protein 1A (SMC protein 1A) (SMC-1-alpha) (SMC-1A) (Sb1.8)
Background: structural maintenance of chromosomes 1A(SMC1A) Homo sapiens Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1B orThe protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation. Mutations in this gene result in Cornelia de Lange syndrome. Altern
Gene Name: SMC1A DXS423E KIAA0178 SB1.8 SMC1 SMC1L1
Protein Name: SMC1 (Ser360)
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基因ID
- 8243
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UniProt
- Q14683
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途径
- Stem Cell Maintenance
抗原
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