SF3B1 抗体 (pThr313)
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北京 101111
Quick Overview for SF3B1 抗体 (pThr313) (ABIN8124907)
抗原
See all SF3B1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pThr313
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原理
- SF3B1 (Phospho Thr313) Antibody
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特异性
- This antibody detects endogenous levels of Human Mouse SF3B1 (phospho-Thr313)
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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免疫原
- Synthesized phosho peptide around human SF3B1 (Thr313)
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亚型
- IgG
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应用备注
- WB 1:500-2000,IHC 1:50-300
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))
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别名
- SF3B1
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背景
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Synonyms: Splicing factor 3B subunit 1 (Pre-mRNA-splicing factor SF3b 155 kDa subunit) (SF3b155) (Spliceosome-associated protein 155) (SAP 155)
Background: This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
Gene Name: SF3B1 SAP155
Protein Name: SF3B1 (Thr313)
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基因ID
- 23451
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UniProt
- O75533
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途径
- Chromatin Binding
抗原
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