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SF3B1 抗体 (pThr313)

The 兔 多克隆 anti-SF3B1 antibody (ABIN8124907) specifically detects SF3B1 in WB 和 IHC. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN8124907
发货至: 中国
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Quick Overview for SF3B1 抗体 (pThr313) (ABIN8124907)

抗原

See all SF3B1 抗体
SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))

适用

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人, 小鼠

宿主

  • 68
  • 2
兔

克隆类型

  • 44
  • 26
多克隆

标记

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This SF3B1 antibody is un-conjugated

应用范围

  • 56
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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 15
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    • 4
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    pThr313

    原理

    SF3B1 (Phospho Thr313) Antibody

    特异性

    This antibody detects endogenous levels of Human Mouse SF3B1 (phospho-Thr313)

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

    免疫原

    Synthesized phosho peptide around human SF3B1 (Thr313)

    亚型

    IgG
  • 应用备注

    WB 1:500-2000,IHC 1:50-300

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))

    别名

    SF3B1

    背景

    Synonyms: Splicing factor 3B subunit 1 (Pre-mRNA-splicing factor SF3b 155 kDa subunit) (SF3b155) (Spliceosome-associated protein 155) (SAP 155)

    Background: This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],

    Gene Name: SF3B1 SAP155

    Protein Name: SF3B1 (Thr313)

    基因ID

    23451

    UniProt

    O75533

    途径

    Chromatin Binding
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