SPHK1 抗体 (pSer225)
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北京 101111
Quick Overview for SPHK1 抗体 (pSer225) (ABIN8124895)
抗原
See all SPHK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer225
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原理
- SPHK1 (Phospho Ser225) Antibody
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特异性
- This antibody detects endogenous levels of SPHK1 (Phospho-Ser225) at Human, Mouse,Rat
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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免疫原
- Synthesized peptide derived from human SPHK1 (Phospho-Ser225)
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亚型
- IgG
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应用备注
- WB 1:500-2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- SPHK1 (Sphingosine Kinase 1 (SPHK1))
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别名
- SPHK1
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背景
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Synonyms: Sphingosine kinase 1 (SK 1) (SPK 1) (EC 2.7.1.91)
Background: The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],
Gene Name: SPHK1 SPHK SPK
Protein Name: SPHK1 (Phospho-Ser225)
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基因ID
- 8877
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UniProt
- Q9NYA1
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途径
- VEGF Signaling
抗原
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