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SPHK1 抗体 (C-Term)

SPHK1 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB15395 unconjugated
产品编号 ABIN652302
发货至: 中国
  • 抗原 See all SPHK1 抗体
    SPHK1 (Sphingosine Kinase 1 (SPHK1))
    抗原表位
    • 15
    • 9
    • 9
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 313-343, C-Term
    适用
    • 98
    • 43
    • 38
    • 11
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 90
    • 8
    • 1
    克隆类型
    • 86
    • 13
    多克隆
    标记
    • 54
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    This SPHK1 antibody is un-conjugated
    应用范围
    • 70
    • 41
    • 25
    • 17
    • 13
    • 13
    • 13
    • 10
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This SPHK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 313-343 amino acids from the C-terminal region of human SPHK1.
    克隆位点
    RB15395
    亚型
    Ig Fraction
    Top Product
    Discover our top product SPHK1 Primary Antibody
  • 应用备注
    WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    SPHK1 (Sphingosine Kinase 1 (SPHK1))
    别名
    SPHK1 (SPHK1 产品)
    别名
    CG1747 antibody, Dmel\\CG1747 antibody, SK1 antibody, Sphk1 antibody, SPHK1 antibody, F18E5.160 antibody, F18E5_160 antibody, sphingosine kinase 1 antibody, SPHK antibody, 1110006G24Rik antibody, Sk1 antibody, Spk1 antibody, Sphingosine kinase 1 antibody, sphingosine kinase 1 antibody, sphingosine kinase 1 L homeolog antibody, Sk1 antibody, SPHK1 antibody, sphk1.L antibody, Sphk1 antibody
    背景
    SPHK1 is a novel lipid messenger with both intracellular and extracellular functions. Intracellularly, it regulates proliferation and survival, and extracellularly, it is a ligand for EDG1 (MIM 601974). Various stimuli increase cellular levels of SPP by activation of sphingosine kinase (SPHK), the enzyme that catalyzes the phosphorylation of sphingosine. Competitive inhibitors of SPHK block formation of SPP and selectively inhibit cellular proliferation induced by a variety of factors, including platelet-derived growth factor (e.g., MIM 173430) and serum.
    基因ID
    8877
    NCBI登录号
    NP_001136073, NP_001136074, NP_068807, NP_892010
    UniProt
    Q9NYA1
    途径
    VEGF Signaling
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