STAT5B 抗体
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北京 101111
Quick Overview for STAT5B 抗体 (ABIN8124701)
抗原
See all STAT5B 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- STAT5B Rabbit mAb
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特异性
- This antibody detects endogenous levels of STAT5B protein.
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纯化方法
- The antibody was purified by protein A affinity chromatography.
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免疫原
- Recombinant protein (or fragment).
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亚型
- IgG
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anti-Signal Transducer and Activator of Transcription 5B (STAT5B) antibody
KD Validated STAT5B 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 24GB2110 unconjugated Recombinant Antibody
anti-Signal Transducer and Activator of Transcription 5B (STAT5B) (AA 737-787) antibodySTAT5B 适用: 人, 小鼠 WB, IHC, FACS, IP, ICC 宿主: 兔 Monoclonal BLR146J unconjugated Recombinant Antibody
anti-Signal Transducer and Activator of Transcription 5B (STAT5B) (AA 678-787) antibodySTAT5B 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2D1 unconjugated
anti-Signal Transducer and Activator of Transcription 5B (STAT5B) (AA 1-390) antibodySTAT5B 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1C2 unconjugated
anti-Signal Transducer and Activator of Transcription 5B (STAT5B) (AA 1-390) antibodySTAT5B 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 1A1 unconjugated
anti-Signal Transducer and Activator of Transcription 5B (STAT5B) antibodySTAT5B 适用: 人 WB, IF, IHC (p), IHC (fro) 宿主: 兔 Monoclonal unconjugated Recombinant Antibody
anti-Signal Transducer and Activator of Transcription 5B (STAT5B) (AA 40-280) antibodySTAT5B 适用: 人 WB, IHC, ELISA, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 5B (STAT5B) (AA 40-280) antibodySTAT5B 适用: 人 WB, IHC, ELISA, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 5B (STAT5B) (C-Term) antibodySTAT5B 适用: 人, 小鼠, 大鼠 WB, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 5B (STAT5B) (AA 180-229) antibodySTAT5B 适用: 人, 犬, Cow, 马, Pig, 绵羊 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB, 1:2000-1:10000 | IHC, 1:1000-1:5000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
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- STAT5B (Signal Transducer and Activator of Transcription 5B (STAT5B))
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别名
- STAT5B
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背景
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Synonyms: Signal transducer and activator of transcription 5B
Background: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo-or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL) . The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. [provi
Gene Name: STAT5B
Protein Name: STAT5B
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基因ID
- 6777
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UniProt
- P51692
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途径
- JAK/STAT Signaling, RTK signaling, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Activated T Cell Proliferation
抗原
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