SIGLEC-5,SIGLEC-14 (AA 91-140) 抗体
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北京 101111
Quick Overview for SIGLEC-5,SIGLEC-14 (AA 91-140) 抗体 (ABIN8124677)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 91-140
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原理
- Siglec-5/14 Antibody
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特异性
- Siglec-5/14 Polyclonal Antibody detects endogenous levels of Siglec-5/14 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from Sialic acid-binding Ig-like lectin 5/Sialic acid-binding Ig-like lectin 14 at AA range: 91-140
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亚型
- IgG
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anti-SIGLEC-5,SIGLEC-14 (Internal Region) antibody
适用: 人 ELISA, WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-SIGLEC-5,SIGLEC-14 antibody (PE)适用: 人, Chimpanzee FACS 宿主: 小鼠 Monoclonal 1A5 PE
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应用备注
- WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- SIGLEC-5,SIGLEC-14
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别名
- Siglec-5/14
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背景
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Synonyms: SIGLEC5, CD33L2, OBBP2, Sialic acid-binding Ig-like lectin 5, Siglec-5, CD33 antigen-like 2, Obesity-binding protein 2, OB-BP2, OB-binding protein 2, CD170, SIGLEC14, Sialic acid-binding Ig-like lectin 14, Siglec-14
Background: This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion. [provided by RefSeq, Feb 2012],
Gene Name: SIGLEC5/SIGLEC14
Protein Name: Sialic acid-binding Ig-like lectin 5/Sialic acid-binding Ig-like lectin 14
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基因ID
- 8778
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UniProt
- O15389
抗原
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