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SIK2 抗体

The 兔 多克隆 anti-SIK2 antibody is suitable to detect SIK2 in samples from 人 和 小鼠. It has been validated for WB 和 ELISA.
产品编号 ABIN8124531
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for SIK2 抗体 (ABIN8124531)

抗原

See all SIK2 抗体
SIK2 (Salt-Inducible Kinase 2 (SIK2))

适用

  • 46
  • 33
  • 22
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
人, 小鼠

宿主

  • 47
  • 7
  • 2
兔

克隆类型

  • 50
  • 6
多克隆

标记

  • 36
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
This SIK2 antibody is un-conjugated

应用范围

  • 45
  • 24
  • 11
  • 11
  • 9
  • 8
  • 6
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA
  • 原理

    SIK2 Antibody

    特异性

    SIK2 Polyclonal Antibody detects endogenous levels of protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from part region of human protein

    亚型

    IgG
  • 应用备注

    WB 1:500-2000 ELISA 1:5000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    SIK2 (Salt-Inducible Kinase 2 (SIK2))

    别名

    SIK2

    背景

    Background: catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by phosphorylation on Thr-175 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39.,function:Phosphorylates 'Ser-794' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. Inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. AMPK subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 UBA domain.,subunit:Interacts with and phosphorylates TORC2/CRTC2.,

    Gene Name: SIK2 KIAA0781 QIK SNF1LK2

    Protein Name: Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) (SIK-2) (Serine/threonine-protein kinase SNF1-like kinase 2)

    基因ID

    23235

    UniProt

    Q9H0K1
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