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POLR2A/RPB1 抗体

The 兔 单克隆 anti-POLR2A/RPB1 antibody (Clone AB2042) (ABIN8124478) specifically detects POLR2A/RPB1 in WB, IHC, IF, ELISA 和 IP. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN8124478
发货至: 中国
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Quick Overview for POLR2A/RPB1 抗体 (ABIN8124478)

抗原

See all POLR2A/RPB1 (POLR2A) 抗体
POLR2A/RPB1 (POLR2A) (RNA Polymerase II Subunit RPB1 (POLR2A))

适用

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人, 小鼠, 大鼠

宿主

  • 116
  • 20
  • 1
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兔

克隆类型

  • 72
  • 67
单克隆

标记

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This POLR2A/RPB1 antibody is un-conjugated

应用范围

  • 107
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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Immunoprecipitation (IP)

克隆位点

AB2042
  • 原理

    Rpb1 Rabbit mAb

    特异性

    This antibody detects endogenous levels of Rpb1 protein.

    纯化方法

    The antibody was purified by protein A affinity chromatography.

    免疫原

    Recombinant protein (or fragment).

    亚型

    IgG
  • 应用备注

    WB, 1:2000-1:10000 | IHC, 1:50-1:200 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at-20°C. Avoid freeze / thaw cycles.
  • 抗原

    POLR2A/RPB1 (POLR2A) (RNA Polymerase II Subunit RPB1 (POLR2A))

    别名

    Rpb1

    背景

    Synonyms: POLR2A, POLR2, DNA-directed RNA polymerase II subunit RPB1, RNA polymerase II subunit B1, DNA-directed RNA polymerase II subunit A, DNA-directed RNA polymerase III largest subunit, RNA-directed RNA polymerase II subunit RPB1

    Background: This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. [provided by RefSeq, Jul 2008],

    Gene Name: POLR2A

    Protein Name: Rpb1

    基因ID

    5430

    UniProt

    P24928

    途径

    Regulatory RNA Pathways
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