RRM2B 抗体
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北京 101111
Quick Overview for RRM2B 抗体 (ABIN8124381)
抗原
See all RRM2B 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- p53R2 Antibody
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特异性
- P53R2 Polyclonal Antibody detects endogenous levels of p53R2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from the Internal region of human p53R2.
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亚型
- IgG
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anti-Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B) (N-Term) antibody
RRM2B 适用: 人, 小鼠, 大鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B) (AA 3-84) antibodyRRM2B 适用: 人 IF 宿主: 小鼠 Monoclonal 6C1 unconjugated
anti-Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B) (AA 1-351) antibodyRRM2B 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B) (AA 128-157) antibodyRRM2B 适用: 人 WB 宿主: 兔 Polyclonal RB36901 unconjugated
anti-Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B) (AA 3-84) antibodyRRM2B 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 6C1 unconjugated
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))
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别名
- p53R2
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背景
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Synonyms: RRM2B, P53R2, Ribonucleoside-diphosphate reductase subunit M2 B, TP53-inducible ribonucleotide reductase M2 B, p53-inducible ribonucleotide reductase small subunit 2-like protein, p53R2
Background: This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010],
Gene Name: RRM2B
Protein Name: Ribonucleoside-diphosphate reductase subunit M2 B
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基因ID
- 50484
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UniProt
- Q7LG56
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途径
- p53 Pathway, Negative Regulation of intrinsic apoptotic Signaling
抗原
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