RIN2 抗体 (AA 70-150)
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北京 101111
Quick Overview for RIN2 抗体 (AA 70-150) (ABIN8124238)
抗原
See all RIN2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 70-150
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原理
- RIN2 Antibody
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特异性
- RIN2 Polyclonal Antibody detects endogenous levels of protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human protein . at AA range: 70-150
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亚型
- IgG
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应用备注
- WB 1:500-2000 ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- RIN2 (Ras and Rab Interactor 2 (RIN2))
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别名
- RIN2
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背景
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Background: The RAB5 protein is a small GTPase involved in membrane trafficking in the early endocytic pathway.The protein encoded by this gene binds the GTP-bound form of the RAB5 protein preferentially over the GDP-bound form, and functions as a guanine nucleotide exchange factor for RAB5. The encoded protein is found primarily as a tetramer in the cytoplasm and does not bind other members of the RAB family. Mutations in this gene cause macrocephaly alopecia cutis laxa and scoliosis (MACS) syndrome, an elastic tissue disorder, as well as the related connective tissue disorder, RIN2 syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011],
Gene Name: RIN2 RASSF4
Protein Name: Ras and Rab interactor 2 (Ras association domain family 4) (Ras inhibitor JC265) (Ras interaction/interference protein 2)
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基因ID
- 54453
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UniProt
- Q8WYP3
抗原
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