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RIN2 抗体 (AA 70-150)

This 兔 多克隆 antibody specifically detects RIN2 in WB 和 ELISA. It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN7231058
发货至: 中国
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Quick Overview for RIN2 抗体 (AA 70-150) (ABIN7231058)

抗原

See all RIN2 抗体
RIN2 (Ras and Rab Interactor 2 (RIN2))

适用

  • 10
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
人, 小鼠

宿主

  • 6
  • 4

克隆类型

  • 7
  • 3
多克隆

标记

  • 10
This RIN2 antibody is un-conjugated

应用范围

  • 10
  • 5
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 70-150

    原理

    Rabbit Anti-RIN2 Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of RIN2 protein

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from part region of human RIN2 protein at AA range: 70-150

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    RIN2 (Ras and Rab Interactor 2 (RIN2))

    别名

    RIN2

    背景

    Ras and Rab interactor 2, Ras association domain family 4, Ras inhibitor JC265, Ras interaction/interference protein 2The RAB5 protein is a small GTPase involved in membrane trafficking in the early endocytic pathway. The protein encoded by RIN2 (Ras And Rab Interactor 2) binds the GTP-bound form of the RAB5 protein preferentially over the GDP-bound form, and functions as a guanine nucleotide exchange factor for RAB5. The encoded protein is found primarily as a tetramer in the cytoplasm and does not bind other members of the RAB family. Mutations in RIN2 cause macrocephaly alopecia cutis laxa and scoliosis (MACS) syndrome, an elastic tissue disorder, as well as the related connective tissue disorder, RIN2 syndrome. Alternative splicing results in multiple transcript variants.

    分子量

    98kD

    基因ID

    54453

    UniProt

    Q8WYP3
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